BPC-157 is a great option to utilize in peptide therapy to help alleviate joint pain, old injuries, and those looking to improve joint mobility.

Some potential benefits of peptide therapy with BPC-157 include:

• Improved wound healing (muscle, ligament, tendon, nerve)
• Anti-inflammatory
• Has been shown to decrease pain in injuries and damaged areas
• Increases growth hormone receptors
• Promotes the outgrowth of tendon fibroblasts, cell survival under stress, and the migration of tendon fibroblasts – leading to improved healing
• Improves digestive function
• May improve blood pressure and nitric oxide production
• Protects and heals inflamed intestinal epithelium (leaky gut)
• It has also been shown to help with Inflammatory Bowel Syndrome (IBS)

BPC-157 is a partial sequence of body protection compound (BPC) that was discovered in and isolated from human gastric juice. Experimentally, it has been demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing, and it may cause superior healing of damaged ligaments.

In addition, BPC-157 seems to protect organs and prevent ulcers of the stomach. BPC-157 acts systemically in the digestive tract to combat leaky gut, IBS, cramps, and Crohn’s disease.

This peptide may also be ideal for nagging injuries where the tissue needs to be rejuvenated.

Those who suffer from discomfort due to muscle sprains, tears, and damage may benefit from this peptide treatment. It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues.

It appears to work by accelerating the rate of angiogenic repair. Angiogenesis is a key dynamic process for wound healing as it allows the formation of new blood vessels from old ones and is involved in the organization of a microvascular network.

Overall, BPC-157 is a great option to help alleviate joint pain, old injuries, and those looking to improve joint mobility.

DSIP or Delta Sleep Inducing Peptide has been used in peptide treatment for poor sleep, pain conditions, and stress-related symptoms

Potential benefits of DSIP:

• Can restore disturbed sleep patterns
• Can modulate cortisol production
• Can reduce persistent/chronic pain

Delta Sleep Inducing Peptide (DSIP) is a well-known neuromodulator and natural sleep generating peptide of 9 amino acids that also has many other physiologic functions. It is typically found in the brain and easily passes the blood-brain barrier. It is mainly prescribed for the treatment of insomnia, pain diseases, alcohol and opioid withdrawal, stress-related symptoms, low testosterone, and even sometimes as an antioxidant and antioncogenic protein.

It has been discovered and heavily studied for over 40 years, yet the mechanism of action is still complex and not well categorized.  The results of studies of DSIP and its analogues since its discovery enable one to state with confidence that DSIP is a unique member of the family of peptide neuromodulators. It exhibits a pronounced stress-protective action and decreases stress-induced metabolic and functional disorders in human and animal organisms exposed to the stresses of different natures.  The effects of these short string amino acids are accomplished through the modulating action on central regulatory processes, owing to the systemic antioxidant action, the modulating influence on the activity of GABAergic, glutamatergic, and other neuronal systems, on the expression of early response genes in brain structures, and on the activity of biosynthetic and proteolytic processes

Since the discovery of DSIP a number of studies have been undertaken to test the theory that DSIP may be the primary substance responsible for generating sleep. It is reported to increase the ‘pressure to sleep’ in human subjects who have been injected with small doses and, this, together with its ability to induce delta-wave sleep, led to its consideration as a treatment for insomnia. A number of studies have examined this.

DSIP is more accurately described as a sleep-promoting substance rather than a sedative. There is a modulating effect on sleep and wake functions with greater activity in circumstances where sleep is disturbed. There are minimal effects in healthy subjects who are not suffering from sleep disturbance. DSIP is not a night sedation drug that needs to be given just before retiring. A dose of DSIP given during the course of the day will promote improved sleep the next night and for several nights thereafter.

It has been used for the treatment of poor sleep, pain conditions, stress-related symptoms, low testosterone (via stimulation of LH), and even sometimes as an antioxidant and anti-cancer protein. It exhibits a pronounced stress-protective action and decreases stress-induced metabolic and functional disorders in human and animal organisms exposed to a variety of stresses. It has also been shown in research to improve hormone levels and physical performance.

Melanotan II (MT2) is a peptide that stimulates the melanocytes to induce skin tanning.

Potential benefits of peptide therapy with a Melanocyte Stimulating Hormone:

• The ability to achieve a darker tan with less exposure to UV radiation
• Possible reduction in the risk of Melanoma (skin cancer)
• A possible reduction in the incidence of sun-damaged skin
• Fair skin individuals have the ability to develop a tan through the use of the Melanotan II peptide.
• It can lead to a reduction in body fat
• No sunburn, No tan lines
• No sunless tanning streaks or fake tan removal
• It can increase libido

Melanotan II (MT2) is a peptide that stimulates the melanocytes to induce skin tanning. Melanocyte Stimulating Hormones (MSH) are a class of peptide hormones produced in the pituitary gland that stimulate melanocytes (pigment-producing cells) in the skin and hair to produce and release melanin which leads to darker skin and hair.

Melanin is the skin pigment produced that protects our skin from the sun’s ultraviolet (UV) radiation and damage. It’s like our body is producing its own natural sunscreen. Pale skin with low levels of melanin makes the skin highly susceptible to DNA damage with excess sun exposure. This lack of melanin and its protection against UV radiation means that those individuals with fair skin have the propensity to burn and risk more DNA damage. It also means that these individuals must take great care to make sure that they tan safely without burning.

To get a safe tan, we need to stimulate the melanocyte-stimulating hormone that is responsible for increasing melanin production. Scientists discovered the use of a “tanning peptide” when investigating possible ways to treat skin cancer. They figured that by inducing the body’s natural pigmentary system through the process of melanogenesis, a protective tan could be produced before UV exposure, thereby reducing the potential for skin damage. With just a little UV exposure, the release of a Melanocyte Stimulating Hormone (MSH) stimulates a natural increase in the production of melanin from the melanocytes in the skin. The use of the tanning peptide provides more MSH, which results in more melanin being produced and greater tanning potential (skin pigmentation) regardless of your skin type.

(Interesting note: During clinical trials for its use as a tanning agent, Melanotan II was found to be a potent stimulator of male erections, thereby enhancing male sexual health. It has also been shown to increase female sexual desire in patients with sexual arousal disorder, and it has now been developed into another unique peptide called Bremelanotide or PT-141).

PT-141/Bremelanotide works for both men and women to improve sexual health and function.

Both men and women might benefit from Bremelanotide or PT-141.  Those that experience

•  Lack of desire or lack of receptivity to sexual activity (both men and women)
•  Inability to become aroused (both men and women)
•  Decreased sensation (women)
•  Pain with intercourse (women)
•  Inability to achieve an orgasm (both men and women)
•  Emotional issues such as embarrassment, shame, anxiety, and a reduced interest in sex (women)
•  Erectile Dysfunction (men)

Bremelanotide (PT-141) was developed from the peptide hormone Melanotan II. In initial testing, Melanotan II-induced darkening of skin pigment, but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects. Further testing in animals showed Bremelanotide to induce lordosis (a sexual mating behavior) and subsequently tested for its effect in humans. Although, most of the research has been targeted to women with female sexual dysfunction, and it is effective medication in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire via the nervous system.

It is estimated that 43% of women (30 million in the US) suffer from sexual dysfunction, and 30 million men suffer from ED, with incidence increasing 2-3 fold between ages 40-70.  Bremelanotide currently has no contraindications and is 80% effective in people who don’t respond to Viagra or Cialis.

Thymosin Alpha-1 (TA-1) is responsible for restoring immune function, particularly cell-mediated immune response.

Potential benefits of peptide therapy with Thymosin Alpha-1 include:

• Enhances the function of certain immune cells called T and dendritic cells
• Effective for acute and chronic infections
• Help eradicate the unhealthy cells and stop the infection or cancer growth
• Exhibits antibacterial, antiviral and antifungal properties
• Suppresses tumor growth
• Increases vaccine effectiveness
• Protects against oxidative damage

Thymosin Alpha-1 (TA-1) is a peptide or very small protein that is responsible for restoring immune response, particularly cell-mediated immune function. Recent studies suggest that the Thymosin Alpha-1 molecule has a major immunoregulatory role.

The drug is in Phase III trials for the treatment of hepatitis C and in Phase II trials for hepatitis B. Additional possible indications are malignant melanoma, hepatocellular carcinoma, drug-resistant tuberculosis, and Di George’s syndrome as well as any chronic cancer or viral disease. Some physicians are using thymosin for chronic fatigue and Lyme disease as well.

It is already approved in more than 37 countries for the treatment of hepatitis B and hepatitis C, and as an adjunct to chemotherapy and various vaccines. TA-1 has been found to have a profound effect on the immune system and is the active ingredient in the immune-modulating drug, Zadaxin®. Zadaxin® is used to treat hepatitis B and C and has been studied extensively for its ability to support an immune system that has been suppressed by chemotherapy in cancer patients.

In addition to its use in the treatment of Hepatitis, AIDS, and cancer, TA-1 has shown great promise in the treatment of Lyme disease. This is unsurprising when one considers the large role the immune system plays in combating the disease.

TA-1 assists the immune system in the location and eradication of the Lyme bacteria and infected cells while helping to prevent oxidative damage, thereby decreasing inflammation and enabling a better quality of life throughout treatment.

Epithalon is thought to improve longevity by restoring telomere length.

Potential Benefits of Epithalon:

• Regulates cell cycle through telomerase activity up-regulation
• Increases and restores telomere length
• Improves glucose tolerance and decreases insulin and triglyceride levels
• Improvement in sleeping patterns
• Activates chromatin for DNA protections